About

The major goals of our research are to characterize the individual proteases (primarily from the cathepsin family) and their inhibitors (stefins, cystatins and related proteins) and to unravel the molecular mechanisms of processes leading to programmed cell death or regulating the immune response of the organism. In addition, our research is focused towards understanding the roles of proteases in various pathological processes, such as cancer, rheumatoid arthritis and osteoarthritis, and different neurological disorders (Huntington disease, …).

News

Article in Cells: Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice

In collaboration with the colleagues from the Faculty of Medicine and Faculty of Chemistry and Chemical Technology, University of Ljubljana, we published a paper entitled: Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice (Cells2021, 10(8), 2071; https://doi.org/10.3390/cells10082071) Abstract Cystatin C is a potent cysteine protease inhibitor that plays an important role …

Open PhD Position

2 full-time PhD positions are open at the Department of Biochemistry, Molecular and Structural Biology at Jožef Stefan Institute, starting on October 1, 2021. We are looking for a highly motivated and enthusiastic candidate with master’s degree in biochemistry or closely related field. Application and additional information: georgy.mikhaylov@ijs.si and veronika.stoka@ijs.si.

Student Info

The Department for Biochemistry and Molecular and Structural Biology offers master’s students, who are interested in conducting a master’s research project in the discipline of Biochemistry, a variety of opportunities.
Become a member of a dynamic team and choose your career in one of the following disciplines.