Proteolytic processing is one of the most important irreversible posttranslational protein modifications, since it affects a great variety of physiological processes critical for life, including the immune response, cell cycle, cell death, and protein and organelle recycling. Proteases are strictly controlled and imbalances in their activities have been found to be critical in a number […]
The proposed “Structural biology” program follows the premise that physiological processes can be reproduced in vitro once we know all molecular components and understand their properties and interactions. Such understanding requires insight in the molecular mechanisms from the points of view of structural, molecular, and computational biology. It is the atomic 3-dimensional structures of macromolecules […]
Marija Grozdanić je v sredo, 20. 12. 2023, pridobila naziv doktor znanosti z uspešnim zagovorom doktorske disertacije z naslovom »Vpliv katepsinske cepitve receptorja za epidermalni rastni dejavnik (EGFR) na signalizacijo rakastih celic«. Iskrene čestitke!
Our coworkers Marija Grozdanić, Barbara Sobotič (joint first authorship), Monika Biasizzo, Tilen Sever, Robert Vidmar, Matej Vizovišek, Boris Turk and Marko Fonović have successfully submitted a research paper titled “Cathephisn L mediated EGFR cleavage affects intracellular signalling pathways in cancer” in the journal Biological Chemistry. In the study, the authors confirmed EGFR as a cathepsin […]
Congratulations to our colleague Matej Kolarič, who received the award for the best poster at the 15th Meeting of the Slovenian Biochemical Society in Portorož, entitled PeptideVisualizer: A novel software solution for PROTOMAP-based determination of protease substrates.
Prof. Aneta Szymańsk Department of Biomedicinal Chemistry, Faculty of Chemistry, University of Gdańsk, Poland 28. 9. 2023 – 10:15 – B220 Human cystatin C (hCC) is associated with physiological and pathological processes in human organism. It functions mainly as an inhibitor of cysteine proteases, but also exhibits neurodegenerative and neuroprotective properties. The wild-type protein modulates […]
Odprt je razpis za kandidatke in kandidate za mlade raziskovalke in mlade raziskovalcepri izbranih mentoricah in mentorjih v letu 2023. Več informacij najdete na naslovu: https://mr.ijs.si/ Rok za prijavo: 5. julij 2023.